Chisa Yukizome begins her job as homeroom teacher for Hope's Peak Academy's 77th Class of Ultmate students. Meanwhile, Hajime Hinata, a student of the school's Reserve Course for students without talent, prepares to undergo an experiment to make him the Ultimate Hope. What follows is a series of tragic events which lead to the birth of the Remnants of Despair and the realization of "The Biggest, Most Awful, Most Tragic Event in Human History."<br> <br><br> <i>Aired alongside of Danganronpa 3: Mirai-hen, with Mirai-hen starting first.</i>